Diagnosis of malaria by polymerase chain reaction.
Enviado por Adelfa Serrano-Brizuela el
Título | Diagnosis of malaria by polymerase chain reaction. |
Publication Type | Journal Article |
Year of Publication | 1999 |
Autores | Ferrer-Rodríguez, I, Vázquez, GJ, Córdova, GJ, Serrano, AE |
Journal | P R Health Sci J |
Volume | 18 |
Issue | 2 |
Pagination | 99-103 |
Date Published | 1999 Jun |
ISSN | 0738-0658 |
Palabras clave | Animals, Base Sequence, Blood, DNA, Protozoan, Electrophoresis, Agar Gel, Female, Humans, Malaria, Falciparum, Middle Aged, Molecular Sequence Data, Plasmodium falciparum, Polymerase Chain Reaction, Travel |
Abstract | Malaria is no longer endemic in Puerto Rico, however, imported cases of the disease are occasionally reported to the Health Department of the Island. This is a report of a 45-year-old female patient who traveled to Kenya and Niger and was admitted to a San Juan area hospital with an 8 day history of daily chills and fever, myalgia, nausea and vomiting. Upon admission, peripheral blood displayed multiple intra-erythrocytic ring-shape trophozoites, highly suggestive of Plasmodium falciparum. The polymerase chain reaction was used as a complementary method for the detection of malaria parasites and confirmation of post-treatment parasite clearance. This report presents an imported case of malaria in Puerto Rico and showed the use of a molecular technique to diagnose Plasmodium. |
Alternate Journal | P R Health Sci J |
PubMed ID | 10461315 |
Grant List | 1F34GM19557-01 / GM / NIGMS NIH HHS / United States GM08224 / GM / NIGMS NIH HHS / United States PR03051 / PR / OCPHP CDC HHS / United States |