Dietary pharmacological or excess zinc and phytase effects on tissue mineral concentrations, metallothionein, and apparent mineral retention in the newly weaned pig.
Enviado por Michelle Martínez Montemayor el
Título | Dietary pharmacological or excess zinc and phytase effects on tissue mineral concentrations, metallothionein, and apparent mineral retention in the newly weaned pig. |
Publication Type | Journal Article |
Year of Publication | 2005 |
Autores | Martínez, MM, Link, JE, Hill, GM |
Journal | Biol Trace Elem Res |
Volume | 105 |
Issue | 1-3 |
Pagination | 97-115 |
Date Published | 2005 Summer |
ISSN | 0163-4984 |
Palabras clave | 6-Phytase, Animals, Copper, Dietary Supplements, Jejunum, Kidney, Liver, Metallothionein, Swine, Time Factors, Weaning, Zinc, Zinc Oxide |
Abstract | Feeding pharmacological zinc (Zn) to weaned pigs improves growth, and dietary phytase improves P and Zn availability. Metallothionein (MT) increases in the duodenum, kidney, and liver of pigs fed 1000 mg Zn/kg with phytase or 2000 mg Zn/kg with or without phytase when fed for 14 d postweaning. The goal of this study was to determine the effects of feeding pharmacological Zn and phytase on tissue minerals, MT, mineral excretion, and apparent retention. Twenty-four newly weaned pigs (20 d; 7.2 kg) were individually fed twice daily, a basal diet supplemented with 0, 1000, or 4000 mg Zn/kg as Zn oxide, without or with phytase (500 phytase units [FTU]/kg) for 14 d, followed by a basal diet (100 mg Zn/kg) without phytase for 7 d. Pigs fed 4000 mg Zn/kg without phytase had higher (p=0.01) plasma, hepatic, renal Zn, renal Cu, and hepatic, renal, and jejunal MT than pigs fed the basal diet or 1000 mg Zn/kg. Duodenal MT was higher (p=0.0001) in pigs fed 1000 and 4000 mg Zn/kg than in pigs fed the basal diet. In pigs fed 1000 and 4000 mg Zn/kg, Zn loading occurred during the first 11 d of supplementation; by d 14, excess Zn was being excreted in the feces. |
DOI | 10.1385/BTER:105:1-3:097 |
Alternate Journal | Biol Trace Elem Res |
PubMed ID | 16034157 |