Endocytosis of neurotransmitter receptors: location matters.
Enviado por Guillermo Yudowski el
PDF version| Título | Endocytosis of neurotransmitter receptors: location matters. |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Autores | Puthenveedu, MA, Yudowski, GA, von Zastrow, M |
| Journal | Cell |
| Volume | 130 |
| Issue | 6 |
| Pagination | 988-9 |
| Date Published | 2007 Sep 21 |
| ISSN | 0092-8674 |
| Palabras clave | Animals, Carrier Proteins, Clathrin, Clathrin-Coated Vesicles, Coated Pits, Cell-Membrane, Dendrites, Dynamin III, Endocytosis, Excitatory Postsynaptic Potentials, Humans, Multiprotein Complexes, Neuronal Plasticity, Protein Transport, Receptors, AMPA, Synapses, Synaptic Vesicles |
| Abstract | Endocytosis of excitatory glutamate receptors from the postsynaptic plasma membrane plays a fundamental role in synaptic function and plasticity. In a recent study published in Neuron, Lu et al. (2007) describe protein interactions that link zones of receptor endocytosis directly to the postsynaptic scaffold and propose that local trafficking of receptors facilitated by these endocytic zones is required to maintain synaptic responsiveness. |
| DOI | 10.1016/j.cell.2007.09.006 |
| Alternate Journal | Cell |
| PubMed ID | 17889644 |
| Grant List | K99 DA023444 / DA / NIDA NIH HHS / United States K99 DA023444-02 / DA / NIDA NIH HHS / United States |
