Bienvenidos a CienciaPR, una red de recursos para todos los interesados en las ciencias y en Puerto Rico.
My current research aims to elucidate the cellular and molecular . My research and training combine methods such as genetic labeling of specific cell types, rabies virus transsynaptic circuit mapping, recordings of neural activity using genetically encoded calcium sensors and electrophysiological methods to understand these mechanisms.
As an independent investigator, my lab has recently expanded to understand the contribution of specific neuroimmune genes to the wiring of developing prefrontal cortex networks. Using targeted genetic manipulation, we have obtained some exciting results, linking increased levels of C4A to aberrant synaptic plasticity in the prefrontal cortex and deficits in social behavior in rodents. The manuscript for this story has now been uploaded on the bioRxivs website: https://www.biorxiv.org/content/10.1101/598342v1. Understanding the mechanisms that guide neural circuit formation in the developing brain is important because it may help establish unifying principles for neural computations and facilitate the development of therapeutic interventions for abnormal network function as is found in schizophrenia and autism.
Recursos relacionados a publicaciones científicas
Encuentra los últimos anuncios de fondos del NIH y el NSF aquí
Mira los últimos anuncios de trabajo de varias fuentes