RIIPLRT Institute: A Respiratory and Immunology Project and Laboratory Research Team (https://www.riplrt.com)
Vision: provide further insight into the immuno-physiological health effects that airborne pollutants of different chemical origins induce once they cross the human respiratory barrier among susceptible individuals such as people suffering from asthma, respiratory allergies, and other chronic respiratory conditions in a collaborative environment that fosters knowledge enrichment and self-discovery in the professional, personal, and academic aspects of the RIPLRT members, collaborators, mentees, and interns.
Mission: We seek to address our scientific questions by integrating human-based immuno-physiological approaches, molecular biology, and computational biology. Also, we will identify opportunities to collaborate, employ, and enhance our expertise in respiratory health, immunology, and data analytics. Lastly, implementing our core values, for example, inclusiveness, diversity, and integrity, will be essential in following our vision and mission.
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Vistazo A La Ciencia / A Glance at the Science (https://www.vistazoalaciencia.com)
Vision: Eliminate barriers between science and society so that citizens can make decisions that contribute to their personal, intellectual, and social well-being.
Mission: Discuss current science topics with the general public through simple presentations and interviews with experts in the field, collaborate with other science communication groups, and encourage minority participation and mentoring in leadership efforts and science communication.
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Endemic Outdoor Aeroallergens and the Incidence of COVID-19 in Puerto Rico
This study aims to determine the role of outdoor fungal spores, aeroallergens endemic in the atmosphere of Puerto Rico, in the incidence and immunological susceptibility to COVID-19 in Puerto Rico. Also, this project seeks to demonstrate the utility of an innovative blood microsample approach to determine immunological risks to emerging respiratory health pathogens, such as the SARS-CoV-2 virus. The expected impact of this project is that it will provide data on immunological risks to emerging respiratory health hazards from exposures to endemic biological aerosol.
Project Number (and PI): PI Benjamín Bolaños-Rosero
Role: Co-Investigator
Date: 2021 - Present
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The RECOVER Project (Research on the Epidemiology of SARS-CoV-2 among Essential Response Personnel)
The RECOVER study aimed to achieve two key objectives: (1) assess the frequency of SARSCoV-2 infection, re-infection, and COVID-19 illness among healthcare workers, first responders, and essential or frontline workers, and (2) evaluate the effectiveness of COVID-19 vaccines and interventions. The anticipated impact of this project was multifaceted. It aimed to measure COVID-19 incidence, identify risk factors for both symptomatic and asymptomatic infection, describe the symptomatology and outcomes of infection and re-infection, and assess healthcare utilization, immune response, and antibody correlates of protection against re-infection. Additionally, the study intended to determine the duration of viral shedding and evaluate knowledge, attitudes, and practices related to SARSCoV-2 and COVID-19.
Project Number (and PI): PI Alberto Cabán-Martínez
Amount Awarded: $3,950,000 (three-year funding)
Role: Lead Scientist and Co-Investigator
Date: 2020 - 2023
Immune and Epigenetic Signatures Related to Post-Hurricane Maria Indoor Contamination in Puerto Rico
This study aimed to identify immune and epigenetic profiles induced by indoor dust samples from flooded homes among Puerto Ricans who lived on the island compared to those who migrated before Hurricane Maria. We seek to identify the immune-epigenetic modulating potential of exposure to Hurricanes and their aftermath pollution.
Project Number (and PI): R25HL126140 (Multi-PI Joe Garcia, Francisco Moreno, Sairam Parthasarathy)
Amount Awarded: $14688 (Pilot Study under a training component of the R25HL126140)
Role: PI of Pilot Study
Date: 2019 - 2022
Linking Microbial, SVOC, and Pro-Inflammatory Exposures in Homes to Childhood Asthma Serverity: A Community Filter Forensics Approach
This project aimed to determine the relationship between urban homes’ characteristics, indoor microbiome, SVOC concentrations, and children’s asthma severity. We also wanted to assess the pro-inflammatory potential of HVAC filter dust and if a community-engaged approach could rapidly and economically assess home exposures and asthma-specific health outcomes in larger cohorts. The cohort consisted of urban homes (low-income and Hispanics) in Austin, TX, followed by a larger campaign of 200 low-income homes of children with asthma in different climate zones of the US.
Project Number: HUD FR-6200-N-15 (PI Kerry Kinney)
Role: Collaborator (PI of a Subaward to Larkin University, $77,000)
Date: 2019 - 2022
Taking a Breath After the Disaster: Homes, Molds, and Health in Puerto Rico after Hurricane Maria
This interdisciplinary and collaborative project aimed to identify the factors affecting human health in the aftermath of a major atmospheric phenomenon, such as Hurricane Maria. We employed microbiome metagenomics, human-based immunological approaches, and community outreach strategies to address this purpose. The institutions collaborating on this project were the University of Puerto Rico, the University of Texas-Austin, and Larkin University.
Project Number: 5R21ES029762-02 (PI Humberto Cavallin)
Role: Collaborator (PI of a Sub-Award to Larkin University; $15,500)
Date: 2018 - 2022