La Fundación Nacional de Ciencias (NSF por sus siglas en inglés) y los Institutos Nacionales de Salud (NIH) han hecho varios llamado a la comunidad científica para recibir propuestas sobre la transmisión del Zika y los efectos a la salud. Las peticiones tienen urgencia, y buscan revisar y otorgar fondos lo más pronto posible. El NSF en particular tiene planes de acelerar la revisión y otorgación de fondos para propuestas meritorias. Para el NSF propuestas que puedan dar algunos resultados en menos de una año tienen prioridad
Abajo compartimos los enlaces y el texto de los llamados.
Como bien conocen, Puerto Rico ha sufrido varios casos de Zika los cuales se deberían estudiar para ayudar a prevenir y controlar esta epidemia.
Dear Colleague Letter: Zika Virus
February 9, 2016
The Ecology & Evolution of Infectious Disease (EEID) program in the Division of Environmental Biology seeks to develop and test predictive models and to discover the principles governing the transmission dynamics of infectious disease agents.
The purpose of this Dear Colleague Letter is to announce that the EEID program is interested in receiving proposals relevant to the ongoing spread of the Zika virus. Proposals may be submitted through one of two routes: as a submission to the annual call for EEID proposals (http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=5269&org=DEB&from=home) or as a RAPID proposal (see Grant Proposal Guide, Chapter II.D.1).
We are particularly interested in proposals that address the ecological transmission dynamics of Zika virus. Questions may include, but are not limited to: What is the frequency and spatial distribution of Zika virus in insect vectors? What is the rate at which Zika virus is transmitted between vectors and humans? What is the rate at which Zika virus is spreading on a regional to continental scale and can this be modeled and predicted? Which species are vectors/carriers of Zika virus? Which non-human species are hosts of Zika virus and in what frequency and spatial distribution? Can mathematical models of Zika virus transmission dynamics and spatial spread of Zika virus be developed that incorporate the effects of vector control methods?
Before submission of a RAPID proposal, you should send a one-page summary of the research project to email@example.com. That summary should include a statement of how the results of this research would be used to affect management of, or policies concerning, the spread of Zika virus WITHIN THE NEXT 12 MONTHS. Projects with a more extended time line should be submitted to the next EEID deadline.
Proposals that deal with disease etiology, pathophysiology, transmission from mother to fetus, transmission through sexual contact, development of diagnostics, or development of vaccines are not appropriate for submission to the EEID program. The National Institute of Allergy and Infectious Disease has also published a notice of interest concerning research on Zika virus: https://grants.nih.gov/grants/guide/notice-files/NOT-AI-16-026.html. Proposals on these topics, as well as the others addressed in their notice, should be directed to that agency.
NIAID is issuing this Notice to highlight its interest in research on, and product development for, Zika virus (ZIKV).
Areas of high priority include, but are not limited to, the following:
- Basic research to understand ZIKV infection, replication, pathogenesis, and transmission;
- Studies to develop animal models to study ZIKV pathogenesis (especially neurological manifestations and teratogenic potential) and evaluate candidate therapeutics and vaccines;
- Studies on the evolution and emergence of ZIKV including the identification of factors that affect host-range and virulence;
- Virologic and serologic surveillance studies of the distribution and natural history of ZIKV in mosquitos, non-human primates and humans, with particular emphasis on hosts(s) reservoirs and cross-species transmission;
- Basic research on the biology of the mosquito vectors, vector competence studies for replication and transmission of ZIKV, host-virus interaction and studies on novel vector control methods;
- Development of sensitive, specific, and rapid clinical diagnostic tests for ZIKV;
- Development of drugs against ZIKV and broad spectrum therapeutics against multiple flavivirus strains, including structure/function studies of ZIKV proteins with the goal of identifying new therapeutic targets;
- Evaluation of the immune response to ZIKV infection and/or vaccination including cell-mediated and innate immunity;
- Evaluation of the immunological interactions between ZIKV and other flaviviruses (especially dengue and yellow fever virus); and
- Development of effective ZIKV vaccines and vaccination strategies based on evolving knowledge of host/pathogen interactions and identification of relevant biomarkers.
Possible funding opportunities that can be used to pursue these research activities include:
- PA-13-304, Small Research Grant (Parent R03)
- PA-13-303, Exploratory/Developmental Research Grant (Parent R21)
- PA-13-302, Research Project Grant (Parent R01)
- PA-15-269, PHS 2015-02 Omnibus Solicitation of the NIH, CDC, FDA, and ACF for Small Business Innovation Research Grant Applications (Parent SBIR)
For other NIAID funding opportunities that may become available in the coming months, please visit the NIAID Funding Opportunities page:http://www.niaid.nih.gov/researchfunding/ann/pages/opps.aspx.