A postdoctoral position is available in the research group of Prof. Carlos Crespo at the Department of Chemistry at the Case Western Reserve University. The successful candidate will lead a research project devoted to understand the dynamics of protein-mediated photo-cross-link and repair of oxidative damage to DNA in defined protein-DNA model systems. Detailed information about our group research projects may be found at the Case Western Reserve University Faculty website at http://www.case.edu/artsci/chem/faculty/crespo/
The successful candidate is expected to make significant contributions in this exciting area of femtobiology. Our laboratory, as part of the Center of Chemical Dynamics (CCD) at Case, features a state-of-the-art Quantronix tunable, regenerative with multipass Ti:Sapphire amplifier with 100 femtosecond time resolution and three traveling-wave optical parametric amplifiers (TOPAS-FS SH SFG, TOPAS-FS NDFG-1,2 A, and TOPAS-White NB SHS) that provide spectral coverage from 240 nm to 18 microns. Related instrumentation also available at CCD includes a picosecond Stimulated Raman Emission, a nanosecond transient absorption spectrometer, a picosecond time-correlated single photon counting, and a nanosecond FTIR. The experimental work would be supplemented with molecular dynamics simulation and high-level quantum chemical calculations.
Expertise setting up and maintaining femtosecond laser systems is highly desirable. Past research experience in photochemistry or biophysics is helpful, but not essential. A Ph.D. in chemistry, physics, or a related discipline is a requirement. The initial appointment will be for one year, extendable upon mutual agreement. Interested candidates should send a CV, and the names of three professional references, to firstname.lastname@example.org