Research Associate, Senior Positions to Develop New Technologies to Study Combinatorial Gene Regulation

Imagen de Paola Giusti-Rodriguez


Position Description: The overall goal of this position to develop new high-throughput technologies for studying combinatorial gene regulation in the human genome. The position is funded through a recently awarded NHGRI Center of Excellence (CEGS) in Genome Science. The focus of the Duke CEGS is to develop new and high-throughput technologies to investigate how combinatorial gene regulation contributes to human health and disease. A multidisciplinary team of seven Duke principal investigators leads the project. The research associate senior hired for this position will report directly to PI Dr. Tim Reddy or PI Dr. Charles Gersbach.

The successful applicant will lead projects on engineering new and improved CRISPR systems for facile and highly multiplexed genome editing, and deploying those systems to identify gene regulatory mechanisms contributing to a diverse range of human diseases. We are particularly interested in candidates with expertise in genome and epigenome editing; CRISPR-based disease modeling; protein engineering; and/or high-throughput genetics, genomics, or epigenetics studies. The candidate will work with a team of faculty, clinicians, postdoctoral associates, graduate students, and undergraduates conducting research and training on human gene regulation.

Requirements and Expectations: A Ph.D. in genetics, genomics, molecular biology, biochemistry, or related disciplines is required. The appointee must have greater than 5-years of postdoctoral training. The ideal candidate will also have a demonstrated track record of scientific productivity, for example via published manuscripts and/or fellowship funding; experience analyzing data from high-throughput biological experiments; and is excited to work in a highly collaborative and multi-disciplinary research environment. This is a 5-year appointment and will be based in Durham, NC. The position will involve travel to annual CEGS meetings once the COVID-19 pandemic subsides.

Compensation and Benefits: We offer very competitive salary and excellent benefits. Visit the Duke University Office of Postdoctoral Service website at and Duke HR website at for details.

Application: If interested in this position, please apply directly at Duke Careers (Req #74530). Please upload/attach your cover letter that includes contact information for 2-3 references, your CV and Research Statement (one page or longer). Applications will be considered on an ongoing basis.

For questions: Contact Shannon Clarke (

Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status. Duke also makes good faith efforts to recruit, hire, and promote qualified women, minorities, individuals with disabilities, and veterans.



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