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Research in my lab is centered on the implementation of mouse models to investigate the neural correlates of psychiatric diseases associated to fear, stress, and emotional trauma. We focus on the characterizaion of neurophysiological mechanisms in limbic brain regions, such as the prefrontal cortex, hippocampus, amygdala, and nucleus accumbens. We implement methodologies such as in vivo neuronal recordings, neuropharmacology, viral vector-mediated gene transduction, immunohistochemistry, fluorescence imaging, and optogenetic and chemogenetic manipulations.
Safety and survival requires correct predictions of potential dangers in the environment. Better understanding is still needed on how the brain makes these predictions to generate dynamic behavioral responses during distinct situations. My lab implements animal models, neural recordings, and sophisticated tools to examine neural circuit activity and mechanisms.
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