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I am a fourth year student at the University of Puerto Rico-Mayagüez Campus (UPRM) where I am undergoing studies leading to a B.S. in Industrial Microbiology. Currently I research in the field of biophysics in the laboratory of Dr. Belinda Pastrana-Ríos found in the Department of Chemistry at the UPRM. Previously, I worked with Dr. Matias J. Cafaro symbiosis in his lab found in the Department of Biology at the UPRM. My research interests lie in the area of neuroscience, specifically the field of Molecular Neurobiology. I want to use the findings in the pathophysiology of Alzheimer's Disease to generate clinical approaches to prevent, treat or cure this disease. My career goals are entering a MD/PhD program and make a residence in the area of Neurology, followed by a Post-doctorate or a Clinical Fellowship in neurodegenerative diseases. Apart from my clinical and scientific goals, I wish to contribute to the development of the puertorican science community in all of the educational stages as well as the global dissemination of this said community nurtured not only in the island, but also in the United States, where there is a steadily growing density of puertoricans.
My current work focuses in the characterization of a calcium binding protein part of the EF hand superfamily called Human Centrin. This protein has key structural roles in centriole duplication, primary cilia formation and DNA repair processes. Our laboratory elucidates protein-protein interaction interfaces and mechanisms between Human Centrin and its target proteins. Techniques utilized include but are not restricted to: FT-IR, ITC, TFF,AKTA Purifications, SDS-PAGE, crystallization, SONICC, TP-UV, bacterial transformation, DNA isolation and low scale fermentation for overexpression of desired proteins.
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