Synthesis and redox-enzyme modulation by amino-1,4-dihydro-benzo[d][1,2]dithiine derivatives.
Enviado por Cornelis Vlaar el
PDF version| Título | Synthesis and redox-enzyme modulation by amino-1,4-dihydro-benzo[d][1,2]dithiine derivatives. |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Autores | Espinosa, S, Solivan, M, Vlaar, CP |
| Journal | Tetrahedron Lett |
| Volume | 50 |
| Issue | 25 |
| Pagination | 3023-3026 |
| Date Published | 2009 Jun 24 |
| ISSN | 0040-4039 |
| Abstract | A convenient method to prepare a series of benzodithiine derivatives was developed, via the synthesis of cyclic disulfide building blocks containing an amino-group linker. Some of the novel cyclic disulfide compounds are shown to modulate the activity of the redox-enzyme glutathione reductase. |
| DOI | 10.1016/j.tetlet.2009.03.209 |
| Alternate Journal | Tetrahedron Lett. |
| PubMed ID | 20161292 |
| PubMed Central ID | PMC2697396 |
| Grant List | S06 GM008224 / GM / NIGMS NIH HHS / United States S06 GM008224-21 / GM / NIGMS NIH HHS / United States |
