Prefrontal involvement in the regulation of emotion: convergence of rat and human studies.
Enviado por Gregory Quirk el
Título | Prefrontal involvement in the regulation of emotion: convergence of rat and human studies. |
Publication Type | Journal Article |
Year of Publication | 2006 |
Autores | Quirk, GJ, Beer, JS |
Journal | Curr Opin Neurobiol |
Volume | 16 |
Issue | 6 |
Pagination | 723-7 |
Date Published | 2006 Dec |
ISSN | 0959-4388 |
Palabras clave | Amygdala, Animals, Cognition, Emotions, Extinction, Psychological, Fear, Humans, Models, Animal, Neural Inhibition, Neural Pathways, Prefrontal Cortex, Rats |
Abstract | Emotion regulation is a process by which we control when and where emotions are expressed. Paradigms used to study the regulation of emotion in humans examine controlled responses to emotional stimuli and/or the inhibition of emotional influences on subsequent behavior. These processes of regulation of emotion trigger activation of the ventromedial prefrontal cortex and inhibition of the amygdala. A similar pattern of activation is seen in rodents during recall of fear extinction, an example of emotional regulation. The overlap in circuitry is consistent with a common mechanism, and points toward future experiments designed to bridge human and rodent models of emotion regulation. |
DOI | 10.1016/j.conb.2006.07.004 |
Alternate Journal | Curr. Opin. Neurobiol. |
PubMed ID | 17084617 |